Drug Docking and Screening Data Resource (U01)
Limited Submission Program (LSP): This funding opportunity and the Limited Submission Program (LSP) is open to all Texas A&M faculty and principal investigators who meet the eligibility requirements. Texas A&M University and The Texas A&M University System Agencies jointly administer this process to select the proposal(s) that will be submitted to the sponsor in response to this solicitation.
PI Eligibility: Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the program director(s)/principal investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
The proposal will be prepared and submitted by Sponsored Research Services (SRS).
Proposal Limit: 1
Summary: The purpose of this Funding Opportunity Announcement (FOA) is to continue to increase the amount of publicly available, high-quality data describing structures and affinities of protein-drug ligand complexes -data vital for development, validation, and benchmarking of drug docking and screening software. Accurate and robust methods for in silico drug screening are expected to speed drug discovery and reduce drug development cost by focusing experimental efforts on the most promising candidate compounds. The ability to predict side effects resulting from off-target binding and to increase repurposing of existing pharmaceuticals is an additional expected benefit.
This FOA solicits applications to maintain, expand and enhance the existing NIGMS-funded Drug Docking and Scoring Data Resource by (i) maintaining strong working relationships with current and past data donors from the pharmaceutical industry and academia; (ii) recruiting new donors of unique datasets valuable to the docking and screening software effort; (iii) optimizing the value of these datasets by adding a limited amount of carefully chosen new experimental results; (iv) maintaining the existing Data Resource contents and integrating them with new data and with information from other sources, such as the Protein Databank; and (v) making all Resource data freely and efficiently available for use by the in silico drug docking and screening community.
August 30, 2013: ***SHORT TURNAROUND*** Deadline for an internal email of intent including the title of the internal proposal and a one-three sentence description of the project.
Send email of intent to email@example.com
September 6, 2013: Deadline to submit an internal proposal.
All proposals for the LSP must be submitted electronically using the e-proposal on-line application system.
Be prepared to upload your internal proposal. The sections will include a one-three page Research Plan Summary and two-page Bio-sketch.
The e-proposal site is password protected. Texas A&M principal investigators may use their NetID and password to access the system. If you do not have a NetID, click HERE for help to activate your NetID. You will need your UIN and your date of birth.
If you have any questions, please contact: firstname.lastname@example.org or 979.862.2233.
September 20, 2013: Target date for the notifications to PIs of the result of the internal competition.
October 9, 2013: Sponsor deadline for the full application (due by 5 p.m. proposer’s local time).
Internal Selection Procedures:
Texas A&M has established a procedure to identify limited submission opportunities and internally select proposals for Texas A&M submissions. Please contact us if you have any questions about the limited submission process.