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Limited Submission Funding Opportunity for Texas A&M University
High-Impact/High-Risk Research Awards

Cancer Prevention & Research Institute of Texas (CPRIT)

PI Eligibility:
The Principal Investigator (PI) must have a doctoral degree, including M.D., Ph.D., D.D.S., D.M.D., Dr. P.H., D.O., D.V.M., or equivalent, and must reside in Texas during the time the research that is the subject of the grant is conducted.

Institutional Limit:
Texas A&M University is eligible to submit 5 proposals.

Agrilife, TEES and TTI are eligible to submit 2 proposals each.

Institutional Eligibility:
The applicant must be a Texas-based entity. Any not-for-profit institution that conducts research is eligible to apply for funding under this award mechanism.  For this submission, TAMU, AGRILIFE, TEES meet the institutional eligibility to submit proposals to CPRIT. 

This RFA solicits applications for relatively short-term, high-impact/high-risk projects that are especially innovative in nature, exploring new concepts or new avenues of cancer research. CPRIT encourages applications that seek to apply or develop state-of-the-art technologies, tools, and/or resources for cancer research, including those with potential commercialization opportunities. CPRIT expects outcomes of supported activities to directly and indirectly benefit subsequent cancer research efforts, cancer public health policy, or the continuum of cancer care—from prevention to treatment and cure. To fulfill this vision, applications may address any research topic or issue related to cancer biology, causation, prevention, detection or screening, treatment, or cure.

Areas of interest include laboratory research, translational studies, and/or clinical investigations. In that cancers arise from a large number of derangements of basic molecular and cellular functions and in turn cause many alterations in basic biological processes, almost any aspect of biology may be relevant to cancer research, more or less directly. The degree of relevance to cancer research will be an important criterion for evaluation of projects for funding by CPRIT. For example, are alterations in the process in question primarily responsible for oncogenesis or secondary manifestations of malignant transformation? Will understanding the process or interfering with it offer selective and useful insight into prevention, diagnosis, or treatment of cancer? Successful applicants for funding from CPRIT will have addressed these questions satisfactorily.

Applicants may request a total of $200,000 for a period of up to 24 months (2 years), inclusive of both direct and indirect costs. Because of the nature of this funding mechanism, renewal applications will not be accepted. Follow-on applications will not be funded until the time requested for the High-Impact/High-Risk Research Award has passed. Award funds may be used to pay for salary and benefits, research supplies, equipment, and clinical costs. Requests for funds for travel to scientific meetings are not appropriate for this funding mechanism, nor are requests for funds to support construction and/or renovation. State law limits the amount of award funding that may be spent on indirect costs to no more than 5 percent of the total award amount.


March 4, 2011: Deadline for an email of intent, including the names of the PI, title of internal proposal and a 1-3 sentence description of the project.

Send email of intent to

March 7, 2011: Deadline to submit an internal proposal, including signatures of approval from your department head and college dean, to the Office of Research Development for review by the internal selection committee.

Send internal proposal to

March 14, 2011: The Internal Selection Committee will notify PIs of the result of the internal competition.

May 30, 2011: Deadline for the full proposal.

Internal Selection Procedures:
Texas A&M University has established a process to identify limited submission opportunities and internally select applications for Texas A&M submissions.