Botanical Dietary Supplement Research Centers

National Institutes of Health

http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-14-001.html

Limited Submission Program (LSP): This funding opportunity and the Limited Submission Program (LSP) is open to all Texas A&M University faculty and principal investigators who meet the eligibility requirements. Texas A&M and The Texas A&M University System agencies jointly administer this process to select the proposal(s) that will be submitted to the sponsor in response to this solicitation.

Institutional Eligibility: Only one application per institution is allowed.

PI Eligibility: Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.

The proposal will be prepared and submitted by Sponsored Research Services (SRS).

Proposal Limit: 1

Summary: This Funding Opportunity Announcement (FOA) invites applications to support research centers to develop and apply cutting-edge, transdisciplinary approaches to the study of botanicals with relevance to human health, that are found as ingredients in dietary supplements. These centers are expected to synergistically integrate a range of relevant disciplines (e.g., phytochemistry, botany, and expertise utilizing models ranging from in silico through in vitro to in vivo) to conduct innovative research to elucidate the interactions between complex botanical products and human biology. The long-term goal of this program is to support development of the preclinical data required for optimal design of rigorous, definitive clinical research on complex botanical products. Given the extensive resources required for clinical research it is critical that clinical trials of botanicals be supported by solid and extensive relevant preclinical data, especially with respect to mechanisms of action, optimal formulations and dosing, for example. Therefore the focus of these Centers will be on basic and preclinical research. The focus of this FOA is on research on the mechanisms of action of botanicals traditionally used for health maintenance, or on botanicals with strong evidence of promise for improving objective, quantitative measures of organism resilience. Use of relevant vertebrate and invertebrate models is strongly encouraged. A strictly limited number of human subjects research aims, designed to interrogate, e.g., in vivo mechanism(s) of action, safety, pharmacokinetics, or bases of individual differences in metabolism or response, may be included.

Dates:

January 17, 2014: Deadline for an email of intent including the title of the internal proposal and a one to three sentence description of the project.

Send email of intent to limitedsubmissions@tamu.edu

January 22, 2014: Deadline to submit an internal proposal.

All proposals for the LSP must be submitted electronically using the e-proposal on-line application system.

Be prepared to upload your internal proposal. The sections will include a one-three page research plan summary, two-page bio-sketch, and preliminary budget.

The e-proposal site is password protected. Texas A&M principal investigators may use their NetID and password to access the system. If you do not have a NetID, click HERE for help to activate your NetID. You will need your UIN and your date of birth.

If you have any questions, please contact:  shelly.martin@tamu.edu or 979.862.2233.

February 5, 2014: Target date for the notifications to PIs of the result of the internal competition.


April 6, 2014: Sponsor deadline for Letter of Intent.


June 6, 2014: Sponsor deadline for the full application (due by 5:00 p.m. proposer’s local time).  


Internal Selection Procedures:
Texas A&M has established a procedure to identify limited submission opportunities and internally select proposals for Texas A&M submissions. Please contact us if you have any questions about the limited submission process.

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